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As a pioneer in the custom peptide synthesis industry, Peptide 2.0 Inc has the expertise you can rely on to produce from simple peptides to most complex and challenging molecules. With the state-of-the-art facility and an outstanding management team, Peptide 2.0 Inc is able to provide custom peptide service with the best quality and the best value to our customers at unprecedented price .
| Advantages |
| High quality at the most competitive price: |
Unprecedented peptide synthesis price |
| High success rate: |
>99%. |
| Fast delivery time: |
2 weeks for unpurified peptides and 3 weeks for purified peptides. |
| Synthesis: |
Peptides up to 121 amino acids can be synthesized. |
| Quantity: |
From 1mg to kilogram scales. |
| Purities: |
From Crude to >98% purity. |
| Report: |
MS and HPLC results are provided for all purified peptides to ensure purity and confirmation of the identity. |
Peptide 2.0 Inc produces thousands of peptides each year for research and pre-clinical applications. Options include the synthesis of peptides from 2 to 121 amino acids in length with any number of labels and modifications including phosphorylation, acetylation, biotin, and cyclization. Heavy isotype peptides for quantitative protein measurement are available in multiple scales and formats to meet the necessary stringency of specific experiment.
Modifications Includes:
- Acetylation, acylation (e.g. lipopeptides), biotinylation and formylation
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Amidation
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Thioethers, hydroxyethylene isosteres, retro-inverso peptides
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Cyclizations: single or multiple disulfide bridges, head to tail and side chain (lactam bridge, thioether)
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Phosphorylation, sulfation and glycosylation
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Incorporation of chromophores
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Fluorescent dyes/fluorogenic groups
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Fluorophore/quencher pairs
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Conjugation to a carrier protein
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Incorporation of D-enantiomers and unusual amino acids
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Labeling with stable isotopes and radiolabeling
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Introduction of C-terminal alcohol moieties
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Introduction of C-terminal ester and thioester groups
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Depsipeptides
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Stabilizing modifications including PEGylation, N-methylated amino acids and reduced peptide bonds
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Ligations
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Hydrocarbon-stapled peptides
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Conjugation of cytotoxic molecules
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Incorporation of chelating moieties (DOTA, DPTA)
Peptide Synthesis at Peptide 2.0 Inc:
Synthetic peptides have emerged as highly versatile tools, useful in a broad range of research and commercial applications. Initially, synthetic peptides were primarily designed to mimic protein epitopes and used as an antigen to generate antibodies. Functional uses of peptides have matured as recent advancements in chemical peptide synthesis and the inclusion of modified amino acids have increased the research options and commercial potential of peptides. Subsequently, longer peptides have been synthesized using refined solid phase chemical synthesis techniques. These techniques combined with fragment condensation and ligation methods, have allowed for the precise synthesis of peptides over 150aa in length.
In addition to synthesis techniques, modified amino acids are being incorporated into peptides allowing customization of a peptide's chemical profile. For example, these modified amino acids can be used to change the solubility of a peptide or increase its bio-availability for use in therapeutics.
In recognition of the tremendous commercial and academic importance of peptides, Peptide 2.0 Inc. now utilizes the most advanced peptide synthesis techniques and instrumentation available. As a result, Peptide 2.0 Inc. has emerged as a world leader in peptide synthesis by consistently providing the research community with cutting-edge synthesis techniques in combination with a full-range of modification options. With peptide customers in over 30 countries, our products and services are a vital resource for academic communities and commercial organizations worldwide.
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